Off licences, fast food restaurants and abandoned buildings line Gratiot Street in north-east Detroit where the cannabis dispensary 420 Dank stands.

The store is not owner Kim Gaetano’s first foray into the medical marijuana business. The mother of two ran legal marijuana shops in Colorado and Washington before moving to Detroit to be closer to family.

Her shop sells cannabis flowers as well as edible products and has a 24-hour drive-through for patients who find it difficult to get out of their cars, especially in the harsh Michigan winter.

But despite the store’s success, Ms Gaetano and her nine employees may soon be out of business.

New legislation in the city of Detroit prevents medical marijuana dispensaries from being within 1,000ft (305m) of schools, churches, off licences, strip clubs or other dispensaries – and 420 Dank is just 371ft away from an off-licence.

Michigan legalised marijuana for medical use in 2008, but it took years for the state to draw up regulations which are enforced differently county to county.

Ms Gaetano has applied for special permission to stay open citing her compliance with other local codes like fire safety and ID inspections and strong ties to the community.

But even if the store is allowed to stay open it will still face new restrictions. Drive-through sales have been banned and stores cannot open until 10am, cutting into the hours when it caters for people finishing night shifts.